"Goserelin": instructions for use and reviews of doctors

Unfortunately, oncological pathologies of genitalorgans, as well as problems with the reproductive system of both men and women will not surprise anyone. If you do not fight these diseases, then a person can die. "Goserelin," the instruction for the use of which must necessarily be studied by the patient, is precisely intended for the treatment of such diseases.

Form of issue and features of action

So, this preparation is synthetica substitute for gonadotropin-releasing hormone. Long-term use of this drug reduces the amount of estradiol in women and testosterone in men. This allows you to reduce the growth rate of malignant tumors of the prostate, breast, uterine fibroids or completely stop it.

As for the form of release, the "Goserelin"(instructions for use are in the package with the medicine) is sold in depot capsules in syringes-applicators with a protective mechanism. Their capacity is 3.6 mg. In addition, you can find the drug in the form of long-acting capsules injected under the skin. Their capacity in this case is 10.8 mg. They can also be purchased in a special syringe-applicator equipped with a protective mechanism.

The drug has a high bioavailability. The maximum level of concentration in the blood is reached after 1.5-3 hours after admission, depending on the sex of the patient. As for the composition of the product, goserelin itself is the main active substance.

Indications for use

So, in order to start taking "Goserelin", the instruction for use provides such indications:

• Prostate cancer in men.
• Oncological breast disease in women who are in reproductive or pre-menopausal age.
• Endometriosis of the uterus.
• Surgical intervention, which requires preliminary preparation - thinning of the endometrial layer.
• Myoma of the uterus.
• Suppression of the functional activity of the pituitary gland in the event of a future artificial insemination.

What contraindications exist?

As with any medication, there are contraindications to the drug "Goserelin." Instruction for use warns of such prohibitions on taking this medication:

• Too high sensitivity to the drug.
• Allergic reaction.
• Children up to 14 years.
• Lactation.
• Pregnancy (even if it persists, the fetus may subsequently develop pathologies of intrauterine development).
• Bone marrow compression.
• Obstruction of the ureters.

Application features

If the patient needs to use"Goserelin", instructions for use (duration of use is strictly determined by the doctor) should be carefully studied. It contains information about such features of the reception: the capsule is intended for subcutaneous administration. Its localization is the anterior abdominal wall.

If treatment of gynecological pathologies is being performed, the capsule should be taken every month. The dosage is 3.6 mg. To fight prostate cancer, a man is administered 10.8 mg every 12 weeks.

We must not forget that during the first weeks of therapy the patient's state of health worsens, as the level of hormones increases. This is a normal reaction to the drug taken.

The duration of treatment is determined byindividually. With gynecological pathologies, it can be no more than six months. It is important to remember that if the patient is assigned "Goserelin", the instruction does not provide for a repeat course of treatment. The fact is that the drug helps to reduce the density of bone tissue and the development of osteoporosis.

If the capsule was taken for some reasonit is necessary to implement it immediately, as soon as the patient recalls this. Women who missed another medication, there is a risk of uterine bleeding.

What unwanted reactions can occur?

If the patient needs a long timetake a drug such as "Goserelin," the instructions and reviews of other patients will provide an opportunity to understand how it works. Naturally, everyone will be interested in what side effects can cause the drug presented.

In men, such reactions can occur:

• Decreased potency and sexual desire.
• Swelling of the breast and its soreness (not often).
• Violation of ureteric patency.

Women may have these side effects:

• Enhanced sweat secretion.
• Frequent mood changes and depressive condition.
• Headache.
• Dryness of the mucous membranes of the genital organs.
• Strong decrease in sex drive.
• Demineralization of bone tissue, which leads to brittle bones.
• Change of breast size.
• Offensive of menopause (in most cases, monthly bleeding is not restored).

Common to both sexes are also such side effects: rash on the skin, nose infections, increased blood pressure, violation of the heart rhythm.

Special instructions, interaction and feedback

So, if the patient needs to take the drug "Goserelin", the instruction (the composition of the drug is already known) gives such specific instructions:

• Capsules can not be taken together with alcohol, as this enhances the demineralization of bones.
• Do not use anticonvulsant drugs, as well as glucocorticosteroids, together with the drug.

As for the reviews, they talk a lot abouta large number of side effects and poor health in the first weeks of treatment. Not all patients benefit from the drug, although in most cases it is still effective.

If the expert believes that the patient is desirabletake "Goserelin", instructions for use (reviews must be taken into account) should always be at hand for the patient throughout the treatment period. Specialists are unanimous in their opinion: despite the large number of undesirable reactions that occur in almost every patient, the medicine is quite effective.

Special Recommendations

There are situations when, after taking the drug, you need to see a doctor. For example, if:

• There were signs of increased intracranial pressure.
• There were signs of hemorrhage in the pituitary: sudden and severe pain in the head, problems with vision, dizziness, confused speech. These symptoms may appear as early as 2 weeks after the start of therapy.
• There are signs of squeezing the spinal canalor problems with the urinary tract. This is usually indicated by pain in the lumbar region, too difficult movement of the upper and lower extremities, an admixture of blood in the urine. Urination is painful.

There are also some facts that need to be considered before the treatment:

1. The patient's history, which takes into account the presenceosteoporosis, high cholesterol in the blood, as well as the presence of uterine bleeding of incomprehensible nature, thrombosis in the patient and his relatives.
2. The tendency of a person to smoke, because this bad habit contributes to the formation of blood clots.
3. The desire of the patient to have a child in the near future or has already arrived pregnancy.
4. The admission of any medications, even those,which are available without a prescription. It is important to tell the doctor about all the biological supplements that are taken, as well as the herbal decoctions that are used in the treatment.
5. The presence of an allergic reaction to any drugs.

Features of storage and analogues

Like any other drug, "Goserelin" should be stored at room temperature, in a place that is well protected from ultraviolet rays and children.

If the patient is unable to take"Goserelin", instructions for use (analogs can cope with this problem) advises to consult a doctor. Moreover, this drug has a high cost - from 8,000 rubles. for the syringe. Among the analogs can be noted "Zoladex", "Buserelin".

That's all the features of the presented means. Be healthy!