"Digoxin": reviews. "Digoxin" (tablets): instructions for use

Chronic heart failure -a disease that is not uncommon today. Wrong lifestyle, poor nutrition and bad habits contribute to a significant deterioration of well-being in old age. It is not possible to recover completely the work of the heart. But drug therapy allows you to lead a full-fledged lifestyle. Tablets "Digoxin" are popular. The use of the drug should be agreed with the doctor.

Composition and form of release

The drug is offered in the form of small tabletsdiameter. The main active ingredient is digoxin. One tablet contains 250 mg of this component. As auxiliary elements magnesium stearate, lactose monohydrate, corn starch, gelatin, silicon colloid anhydrous, talc are used. The medicine is offered in pharmacies in cardboard packages or plastic bottles.

The drug belongs to the group of cardiac glycosides. Tablets "Digoxin" have a positive effect on heart function. The instruction says that myocardial contractility significantly increases. Thanks to this, the shock volume of blood also increases. In addition, the volume of the heart decreases. This leads to the fact that the need for myocardium in oxygen is significantly reduced.

Patients who suffer from atrial fibrillationtachyarrhythmia, may also use the drug. The main active component slows down the frequency of ventricular contractions, and also improves intracardiac geodynamics.

Pharmacokinetics

Well tolerated by most patientstablets Digoxin. Experts' reviews show that the medicine is perfectly absorbed into the walls of the stomach. As a percentage, this figure is 80%. In many ways, absorption depends on the health of the stomach, as well as the food taken in parallel. Bioavailability of the drug "Digoxin" is 60-70%. If the gastric juice has a normal acidity, only a small amount of the main active substance of the medication is destroyed.

The drug has the ability to accumulate in tissues. Therefore, at the beginning of treatment there is no correlation between the concentration of the drug in the plasma and the severity of the pharmacodynamic effect. The drug is metabolized in the liver, and is excreted mostly by the kidneys. Up to 80% comes out unchanged. If the patient suffers from hepatic impairment, compensation may be due to increased excretion of digoxin by the kidneys.

Indications

Popular in patients and doctors enjoysmedicinal product "Digoxin". The reviews show that the pills help to restore the heart perfectly. Prescribe the drug primarily to patients with chronic heart failure, if there are clinical manifestations of the disease. A positive effect is also exerted on patients who suffer from a tachycystologic form of atrial fibrillation. Especially if this condition is manifested in the background of chronic heart failure.

Can not be used as monotherapy"Digoxin" (tablets). Instruction for use states that the drug can be prescribed only as part of a comprehensive treatment of chronic heart failure. Tablets help to restore the heart rhythm and well-being of the patient. But they can not completely restore the heart to their former condition.

Contraindications

For some patients may be dangeroustablets Digoxin. The doctors' comments show that the medicine should be taken only after a complete examination of the body. The medicine has many contraindications. These include diseases such as Wolff-Parkinson-White syndrome, intermittent complete blockade, glycoside intoxication. In some cases, there may be increased sensitivity to the components of the drug.

There are also states of the body in whichthe use of the drug "digoxin" is possible, but with caution. The specialist should carefully evaluate the possible benefits and harms. It is not recommended without a doctor's consultation to drink tablets in conditions such as hypertrophic subaortic stenosis, acute myocardial infarction, unstable angina, arteriovenous shunt, amyloidosis of the heart.

Use during pregnancy and lactation

Studies were conducted on the subject ofthe possibility of taking "Digoxin" tablets by pregnant and lactating women. It was found that the main active ingredient can penetrate both through the placental barrier to the fetus, and into breast milk. During birth, the concentration of the main component of the drug in the blood serum of the newborn and the mother is absolutely the same. On the safety of the application, the "Digoxin" medication can be classified as "C". Experts' reviews show that during pregnancy and lactation, tablets are recommended only in extreme cases. Do this only when the potential benefit to the mother exceeds the potential risk for the child.

Studies on the subject of taking medication by childrennot conducted. For this reason, "Digoxin" tablets are not prescribed to under-age patients. There are many other drugs that are intended for the treatment of heart defects in children under 18 years of age.

Dosage

It should be taken correctly "digoxin" (tablets). The instructions for use describe the exact dosage for each clinical case. The medicine is taken only inside. It is worth remembering that the tablets belong to the group of cardiac glycosides. Therefore, the dosage should be selected especially carefully in accordance with the individual characteristics of the patient's body. If the patient has previously taken cardiac glycosides, the dosage of "Digoxin" tablets should be reduced.

For adults, the maximum dosage is selected independing on the need to quickly get a therapeutic effect. Rapid digestization can be used only in emergency cases, when the patient's condition deteriorates sharply. In this case, the patient takes 1.25 mg of the drug twice. Before each subsequent dose, an ECG should be performed. As soon as the patient's heart returns to normal, it is necessary to begin maintenance treatment. The dosage can be reduced.

In most cases, patients are shownslow digistalization. It is necessary to take the drug "Digoxin" within 5-7 days. Reviews in heart disease show that this method allows you to maintain a normal state of health for a long time. The daily dosage of the drug can be 250-500 mcg. Tablets are taken only once a day.

Overdose

It should be taken in accordance with the recommendationthe doctor of a tablet "Digoxin". The reviews show that misuse of tablets can lead to an overdose. The main symptoms are worsening of sleep, loss of appetite, dizziness, nausea and vomiting. In some patients, heart function may worsen. Symptoms such as fibrillation and atrial flutter, nodal tachycardia, and sinoatrial blockade appear. The patient may have confusion, decreased visual acuity, psychosis.

Cardinal treatment does not require an overdose. The doctor can only cancel the drug "Digoxin" and prescribe activated charcoal. In case of acute drug poisoning, the patient may be shown gastric lavage. Treatment should take place in a medical institution under the supervision of specialists.

Adverse Events

Poor health in patients most oftenis a consequence of an overdose of "Digoxin" tablets. Instructions for use, testimonials - all this should be studied before starting the medication. Drug intoxication may be manifested by symptoms such as ventricular paroxysmal tachycardia, sinoauric blockade, nodal tachycardia, polytopic ventricular extrasystole. From the side of the digestive system, patients often experience nausea, vomiting and diarrhea. Against this background, patients in rare cases completely refuse to eat. This condition is dangerous by the development of anorexia.

From the central nervous system canthere are such side effects as sleep disorders, headaches, depressive syndrome, confusion, visual hallucinations. If such symptoms occur, immediately stop taking the "Digoxin" tablets. The testimonies of people show that the normal state of the body is returned immediately after the withdrawal of the drug.

Drug Interactions

Any cardiac glycosides should be taken withcaution with other drugs. It is not recommended to drink tablets "Digoxin" together with medications that disrupt the electrolyte balance. To such, first of all, diuretics, insulin, glucocorticosteroids - the risk of toxic effects of the drug "Digoxin" increases. Adverse events can also lead to hypercalcemia. Therefore, it is not recommended for patients to administer calcium salts together with Digoxin. Reviews at atrial fibrillation show that even a small dose of calcium is enough to cause side effects.

Under the influence of drugs containingaluminum, the absorption of digoxin in the intestine can be reduced. As a result, the positive effect of the tablets on the body will be reduced. Also with caution should take spironolactone. It helps to reduce the concentration of digoxin in the serum, and also distorts the results of determining the content of matter in the body.

The conventional activated carbon significantly reducesbioavailability of the drug "digoxin". Feedback on the application shows that the drug is absolutely inactive when used in conjunction with drugs that improve the motility of the gastrointestinal tract.

Are there analogues?

What if the medicine is based onDid not find digoxin in the pharmacy? The doctor can always choose a drug that will have a similar effect on the body. For example, tablets "Cardiomagnolo" are popular. This drug, the main active ingredient of which is magnesium hydroxide. In addition, components such as acetylsalicylic acid, potato starch, magnesium stearate, and microcrystalline cellulose are used.

The medicine "Cardiomagnum" can be prescribed for the treatment of various diseases of the cardiovascular system. It is also accepted as a prophylaxis for thrombosis and repeated myocardial infarction.

Reviews about the drug "Digoxin"

Increasingly with chronic heart diseaseInsufficiency specialists prescribe tablets "Digoxin". The reviews show that the medicine gives really good results when it is used correctly. To avoid any side effects, it should be taken strictly according to the doctor's recommendation. A qualified specialist will always be able to select the desired dosage in accordance with the form of the disease, as well as the individual characteristics of the patient.

Negative reviews of the drug "Digoxin" alsoare available. They are connected, to a large extent, with a large number of side effects. It is worth noting that unpleasant symptoms are manifested most often in those patients who do not comply with the desired dosage or take the drug together with other medicines. It is necessary to use with care tablets "Digoxin". Instructions for use, reviews - all this should be studied before starting therapy.

Where to buy the drug?

The drug is released by prescription. After contacting a specialist, the medicine can be purchased at the nearest pharmacy. Tablets "Digoxin" are not uncommon. Also, the medicine can be ordered in real time. In online pharmacies the medicine costs much less.

How much do you have to pay?

Tablets "Digoxin" refer to a low price category. For one packing it is necessary to pay only about 50 rubles. If you order a drug in an online pharmacy, you will save up to 15%.

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