The drug "Nifedipine": instructions for use

Nifedipine is usedfor the expansion of coronary and peripheral vessels, mainly arterial. It has a negative ionotropic effect, significantly reduces the need for myocardium in oxygen and does not strongly inhibit the conduction of the cardiac system. Reduces pressure and significantly reduces the resistance of peripheral vessels.

The drug "Nifedipine", instructions for usewhich speaks about the ways of its influence on a person, when taken very quickly gets into the blood. Literally after half an hour, its maximum concentration in plasma is observed. But, having a short half-life, equal to 2-4 hours, the substance is rapidly excreted from the body. However, with prolonged taking of the medicine, the organism becomes accustomed to its action.

INDICATIONS: The drug "Nifedipine", the use of which is strictly controlled by a doctor, is usually prescribed for angina pectoris, symptomatic and essential hypertension, to reduce blood pressure.

It is used in the treatment of cardiacinsufficiency, in combination with other drugs, improves the function of the heart, while helping to reduce its size. There was also a decrease in pressure in the pulmonary artery.

There is evidence of a positive effect of the drug "Nifedipine" on cerebral hemodynamics, as well as on the effective use of Raynaud's disease.

For maintenance therapy in combination with other drugs, the drug can be used as a bronchodilator.

APPLICATION: It is applied inside, 3-4 times a day for 10-30 mg,regardless of food intake. When hypertensive crisis can be used as a solution in a dose of 10 mg. If necessary, repeat in half an hour, you can increase the dose to 30 mg or in the amount of 5 mg to administer the drug for 4-8 hours. The maximum dose should not exceed 30 mg.

CONTRAINDICATIONS: The drug is categorically contraindicated in pregnant or lactating.

Tablets "Nifedipine" can not be used for arterial hypotension, pronounced heart failure, porphyria, hypersensitivity to the drug, unstable angina.

Caution should apply the drug to drivers and those whose work requires a quick mental and physical response.

SIDE EFFECTS: Although the drug Nifedipine is usually well tolerated, the instructions for use indicate some side effects.

If the patient appears at the time of taking the medicineunusual drowsiness, progressive headache and dizziness, it is necessary to reduce the dose. Tachycardia, edema of the lower limbs, redness of the skin of the trunk and face, or nausea may also appear. In addition, palpitation is possible, lowering blood pressure.

SPECIAL INSTRUCTIONS: Older people when treated with the drug "Nifedipine" (instructions for use indicate this) should be under the close supervision of a medical professional.

Patients with diabetes, myocardial infarction andunstable angina should use the drug with extreme caution, because the resulting reflex tachycardia can significantly exacerbate the chronic disease.

INTERACTIONS: Medications "Nifedipine" can not be taken simultaneously with other antihypertensive drugs.

The drug should be discontinued one day before the planned anesthesia with fentanyl.

OVERDOSE: In case of an overdose of NifedipineThe instructions for use indicate some symptoms. For example, there is arterial hypotension, heart failure, shock, convulsions. It is recommended that gastric lavage, control of hemodynamic parameters, reception of activated charcoal and symptomatic treatment.

FORM OF ISSUE: The drug is available in tablets coated with a coating and containing 10 mg of the drug, as well as in a solution in vials of 50 ml or 2 ml in ampoules.

STORAGE CONDITIONS: Store in a dark place. Refers to list B.