Prednisone tablets
The package contains 100 tablets, eachwhich contains 5 milligrams of prednisolone. Indications for use are connective tissue diseases, including rheumatoid arthritis, systemic vasculitis, polymyositis, dermatomyositis and lupus erythematosus. Prednisolone tablets are used for rheumatic carditis, acute rheumatism, Addison's disease, acute adrenal insufficiency. The drug shows good results in the treatment of adrenogenital syndrome, bronchial asthma, allergic diseases.
Prednisone tablets are successfully used in hepatitis, hepatic
coma, hypoglycemic conditions, kidney disease of an autoimmune nature.
The drug is also used in diseases of the hematopoietic system,
various forms of leukemia, agranulocytosis, thrombocytopenic purpura,
hemolytic anemia, Hodgkin's disease. Prednisone tablets are also used
for the treatment of skin diseases such as Lyell's syndrome, psoriasis,
exfoliative dermatitis, eczema and pemphigus. Treat the drug with such eye
diseases like choroiditis, uveitis, iridocyclitis, iritis, non-purulent keratitis,
allergic forms of conjunctivitis, sympathetic ophthalmia. Assign
Prednisone tablets with nephrotic syndrome, asthmatic bronchitis, acute rheumatism and small chorea.
As you can see, the preparation has a very wide range of applications. It is well absorbed by the gastrointestinal tract when used
inside. Prednisolone, whose release form in tablets is 5 mg, is metabolized mainly in the liver. About 20% of the drug is excreted by the kidneys. Dosage regimen of prednisolone is established individually. As an overwhelming dose for acute conditions, 5-6 tablets per day are prescribed. The maintenance dose is 1-2 tablets. In some diseases, such as leukemia, rheumatic diseases and nephrotic syndrome, the dose of Prednisolone may be increased.
Prednisolone: side effects
Side effects may be ulcerogenousaction from the gastrointestinal tract. Other manifestations are the occurrence of osteoporosis, arterial hypertension, and a decrease in resistance to infections. In the field of metabolism and endocrine status, there is atrophy of the adrenal cortex, hypokalemia, iatrogenic Cushing's syndrome, steroid diabetes, glucosuria, the presence of a negative nitrogen balance.
Contraindications for Prednisolone is ulcerative
disease, vaccination period, herpes zoster, chicken pox, severe forms
arterial hypertension. Do not use the drug
in diseases caused by the Herpes simplex virus, renal failure,
predisposition to thromboembolism, osteoporosis and Cushing's syndrome.
Prednisolone should be used with a particularcaution in the first trimester of pregnancy. With diabetes, prednisolone is prescribed only with absolute indications or in the treatment of insulin resistance. For
treatment of infectious diseases and tuberculosis. Prednisolone is prescribed only in
combination with tuberculostatic drugs and antibiotics.
With the simultaneous administration of prednisolone andoral hypoglycemic drugs, the dosage regimen of the latter is recommended to be corrected. It is not recommended joint use with barbiturates in patients with Addison's disease, since acute renal failure can occur as an addison syndrome. When combining Prednisolone with diuretics, you need to carefully monitor the electrolyte balance. With prolonged use of Prednisolone for the prevention of hypokalemia
an appropriate diet and calcium preparations are prescribed.
