Premature aging: symptoms and ways of fighting.

Premature aging is a disease that consists in a very sharp and rapid aging of the skin. It is also called progeria, the name is derived from the Greek word progeros.

For the first time openly stated the existence of a problemrapid aging in some children in 1886 in America. I am glad that this disease is very rare, at the moment there are 53 people all over the world who suffer from premature skin aging. There is no adherence to a certain gender, that is, this misfortune can happen both with the boy and with the girl.

Recognize premature aging on earlystages is very difficult, because at birth, the baby is apparently perfectly healthy. The first signs can be identified only after a year or two of life baby. In this case, the development of the main features is characteristic. These include a sharp weight loss and stopping growth, hair begins to fall out, the skin wrinkles. As complications, a dislocation of the femoral part may occur, as the bones become weak. In practice, there have been cases of serious cardiovascular diseases, for example, stroke or heart attack.

Premature aging at the momentis considered one of the most important problems that scientists are still studying, since no reliable cure was found. Life expectancy in patients is very small, and on average it hardly reaches 14 years. The maximum period of residence is 21 years, and it is noted that death, as well as in old people, most often occurs due to the development of cardiovascular pathologies.

Scientists have proved that in 90% of cases such adisease premature aging is a consequence of a mutation in a particular gene. There are violations in the genotype. Transmitted by hereditary pathway such a disease can not, that is, if one child has premature aging, then do not worry about the health of future children and fear the next conception. Of course, there are situations when two relatives fall ill in one family. But scientists classify this as an accident, but not a regularity or heredity. The probability of this incident is only 1 percent of the 100 possible.

The manifestation of the main symptoms, for example, sharploss of weight, and stopping growth, can only natolknut on certain thoughts. Precisely to diagnose premature aging of children the expert can only by means of carrying out of genetic research. As already noted above, there is no clear way to treat this terrible disease, therefore, active work is being done in this area. With progeria, the cell nucleus is destroyed. It is believed that the drug farnesyltransferase, which is designed to treat cancers, is able to restore the cellular structure, including the destroyed nucleus. While experiments were conducted on mice, they showed that there were minor improvements. In the trial, 13 mice participated, who were medicated for three months, with only one lethal outcome.

But the hope of sick children never fades,because the medicine is developing with every day and with seven-league steps moves towards the solution of many important problems. For example, in America, experts have put forward a version according to which the antibiotic rapamycin can become a real obstacle to the active destruction of cells. In ordinary life, it is prescribed to people who plan an organ transplant surgery, since rapamycin reduces the work of the immune system. During numerous experiments and studies it was proved that the composition of antibiotics can gradually stop a rapidly progressing disease. But before the full confirmation he should go through many more checks.