Medication "Ornidazole", analogues of the drug(for example, "Lornisol", "Tiberal", "Avrazor" and others) are antimicrobial and antiprotozoal agents. Medications are used to eliminate and prevent anaerobic infections, giardiasis, trichomoniasis, amoebiasis.
The drug "Ornidazole" (reviews and comments of specialists confirm this) does not inhibit aldehyde dehydrogenase. In this regard (in contrast to the drug "Metronidazole") it is compatible with alcohol.
Means "Ornidazole" after penetration into the digestive tractis sufficiently fast absorbed. The maximum concentration of the drug reaches within three hours. The drug "Ornidazole" penetrates into the cerebrospinal fluid, other tissues and body fluids.
The drug is metabolized in the liver. Half-life is about thirteen hours. After a single application, about 85% of the drug is excreted within the first five days mainly in the form of decay products. Approximately 4% is excreted in urine in unmodified form.
The drug "Ornidazole" (experts' reviews confirm this) is effective in urogenital infections triggered by Trichomonas vaginalis (vaginal trichomonas) in men and women.
The drug is used for amoebiasis (all intestinal infections associated with the activity of Entamoeba histolytica dysentery amoeba, all extraintestinal forms, amoeba abscess in the liver).
The drug "Ornidazole" is also recommended for giardiasis.
The medication is prescribed for the prevention of infections caused by anaerobic on the background of operations on the colon, as well as in gynecology.
The drug "Ornidazole" (experts' reviews confirm this) should be taken only after meals.
With trichomoniasis appoint twice a day for 500 mg (in the mornings and evenings). Treatment lasts five days.
To exclude secondary infection, the sexual partner also needs to undergo a therapeutic course.
For children with this disease appoint a day per kilogram of weight of 25 mg. The received amount of the drug is taken once.
With giardiasis, the drug is prescribed in a dose of 1.5 grams (with a patient weight of more than 35 kilograms) once. Medication is taken in the evening.
For children weighing less than 35 kg, appoint 40 mg per kg per day.
Duration of therapy is one to two days.
In the treatment of anaerobic infections, the drug is taken every twelve hours at a dose of 500 mg.
With amoebiasis, the dosage and dosage regimen is set individually.
Medication "Ornidazole" (doctors' reviews are unequivocal in this) is not prescribed for hypersensitivity.
In the course of various studies involving animalsThere was no toxic or teratogenic effect of the drug on the fetus. However, adequately controlled studies in humans have not been conducted. In this regard, the appointment of the drug to pregnant or lactating women is carried out only on absolute indications.
When taking medication, "Ornidazole" is likelythe emergence of drowsiness (mild), gastrointestinal disorders, headaches. In a number of cases, there was tremor, dizziness, short-term loss of consciousness, coordination disorder. To undesirable manifestations should be attributed and the reactions of individual intolerance, signs of mixed neuropathy.
In case of an overdose, there is an increase in adverse events. In addition, depression develops, epileptiform cramps occur.
At appointment it is necessary to be cautious with patients with pathologies of the CNS (multiple sclerosis, epilepsy, lesions in the brain).
When taking higher doses, there is some risk of developing hepatic dysfunction in patients with liver damage that abusers alcohol, as well as in children, nursing and pregnant women.
The drug "Ornidazole-vero" (reviews of patients testify to this) does not differ in its effectiveness from the above-described medication.
Before using medicines, you should consult a doctor.
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