Ascoril - instructions for use.

Dosage form

The drug is available in the form of syrup and tablets.

The drug, which is presented in the form of a medicinal form of syrup - "Ascoril" for children. The instruction includes the composition of the syrup.

Composition:

Active substance:

• salbutamol - 2 mg (in 10 ml of the drug);
• guaifenesin - 100 mg (in 10 ml of the drug);
• bromhexine hydrochloride - 4 mg (in 10 ml of the preparation);
• menthol - 1 mg (in 10 ml of the drug).

Excipients:

• sorbitol;
• sodium benzoate;
• sucrose;
• flavoring additives;
• glycerol;
• yellow dye sanset;
• propylene glycol;
• purified water.

Ascoril - tablets. The instruction includes the composition of the ascoril tablets.

Composition:

Active substance:

• salbutamol - 2 mg (in 1 table);
• guaifenesin - 100 mg (in 1 table);
• bromhexine hydrochloride 8 mg (in 1 table).

Pharmacological action of the drug "Ascoril"

The instruction says that the ascaril refers tocategory of drugs with expectorant and bronchodilator effect. The pharmacological action of salbutamol is the relief of bronchospasm, as well as bronchodilator action. This is due to the fact that salbutamol is an agonist of beta-2-adrenergic receptors.

The mucolytic action of ascorilum rendersbromhexine, which is able to reduce the viscosity of secreted bronchial secretions, by depolarizing acidic carbohydrates, and by stimulating secretory cells on the bronchial mucosa.

Guaifenesin promotes sphagnum expectoration andthe manifestation of its adhesive properties, and in addition, this substance helps to reduce the surface tension. Menthol gently stimulates the secretion of bronchial glands and has a stable spasmolytic effect. Also, menthol has the properties of an antiseptic and can restore the functionality of the ciliated epithelium located on the bronchial mucosa.

Pharmacokinetics of the drug "Ascoril"

The instruction does not have information aboutpharmacokinetic properties of the drug, perhaps this is due to the difficulty of conducting studies, due to the large number of active properties of the drug.

Indications

• bronchiectasis;
• bronchial asthma;
• bronchitis of chronic or acute form;
• atelectasis;
• pneumonia;
• emphysema;
• tuberculosis;
• whooping cough;
• bronchostatic conditions.

Side effects of the medicine "Ascoril"

The instruction indicates some side effects that may arise from the taking of this drug.

When using the drug are possible:

• tachycardia;
• tremor of hands;
• muscle cramps.

In the case of high doses of the drug:

• headache;
• tachycardia;
• peripheral vasodilation.

Contraindications for the medicine "Ascoril"

The instruction indicates the following contraindications, in which taking the drug is not recommended:

• disturbance of the rhythm of the heart;
• tachycardia;
• Hypersensitivity to components.

Studies in the field of application of ascoril inpregnant women have not been treated, so it is impossible to speak positively or negatively about the effect of this drug on the fetus. Now its use by pregnant women depends solely on the availability of a safer alternative, or the need to choose between the possible consequences for the fetus or the deterioration of the patient's condition.

The drug should not be used simultaneously with the beta blockers.

Patients who suffer from diabetes mellitus, stomach ulcers, severe CCC, duodenal ulcer and hypertension should take this medication with caution.

Overdose

When an overdose of the drug sometimes there are increased side effects. Specific treatment in this case is not available, so the patient should be given symptomatic.

Drug Interactions

In the event that together with the drug are usedtheophylline, and also any sympathomimetics, then the risk of side effects of salbutamol, which is part of the main active agents, is significantly increased.

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