"Drotaverin" from what? "Drotaverin" is "No-shpa"?

For a long time the drug"Drotaverin" is in high demand among patients. The effective work of the drug, proven during multiple clinical trials, allows it to be used as a quick-acting and readily available drug. "Drotaverin" - injections or pills - can be used both once, and in a complex course of therapy for many diseases.

Creature

In 1961, a derivative was developed"Papaverine" is the drug "Drotaverin." In the course of clinical and pharmacological studies, the more effective work of the drug "Drotaverin" in relation to its predecessor was proved.

Drug Drotaverin with itsthe main metabolites is a powerful selective inhibitor of cells of smooth muscle tissue, due to this, not only an anesthetic effect is obtained, but also reduce inflammation and edema of damaged tissues, and on the whole get a positive effect on the functioning of the body. Many patients ask themselves: "Drotaverin tablets are No-shpa?" Yes, No-shpa is an analogue of it, and Drotaverin can also be replaced with many other similar antispasmodic medications.

Drotaverin: what helps

Elimination of spasm is the main function of the drug,however, since pain is only a symptom characterized by physiological and pathological contraction of the muscles accompanied by certain diseases, it means that the drug "Drotaverin" is prescribed together with other medicines. Deterioration of blood circulation of the damaged area can serve as the beginning of the pathological process.

Medical practice has a number of cases in which the use of Drotaverin is required, but the main areas are:

• As a preparatory tool for patients sent to various procedures, for example, on the catheterization of the ureters.
• As symptomatic therapy, when pain is the main characteristic accompanying manifestation of the disease, but does not play a leading role in its pathogenesis.

How the drug works

Therapeutic efficacy of Drotaverinbased on the impact on the mechanisms of muscle contraction. When the cells of the smooth muscle relax, the tension (tone) of the walls of the sexual female organ decreases, the pain in menstruation is significantly weakened or completely eliminated. Thanks to the successful relief of pain, the blood supply to the walls of the organ improves.

Unlike other drugs-analgesics"Drotaverine" does not erase the symptoms of the disease. The drug "Drotaverin" does not require a prescription for its purchase, it can be presented in several forms, the appointment of which should be decided by the attending physician:

• Ampoules of 2 ml contain 40 mg of active ingredient "Drotaverina".
• Tablets with a dosage of 40 mg of active ingredient.
• Forte tablets with increased dosing of 80 mg of the substance.

Drotaverin: the main directions of the drug

With gastrointestinal diseases, it is quite positivethe body is affected by the drug "drotaverin", which weakens the smooth muscles and relieves spasms. The agent can greatly help with the following ailments:

• Colitis.
• Pancreatitis.
• Dysfunction of the sphincter of Oddi.
• Irritable bowel syndrome.
• Not ulcerative indigestion.
• Peptic ulcers of the stomach and duodenal ulcer.
• Papillite.
• Cholangitis.
• Pericholecystitis.
• Cholecystitis.
• Cholelithiasis.

The results of the research showed ...

The drug "Drotaverin": from what it is so useful, and what is its advantage among other drugs? During the testing of the drug and clinical studies aimed at studying the effect of the medication on patients diagnosed with the stenosis of the sphincter of Oddi, a significant weakening of the syndrome in 60% of all subjects was noted. In this case, the more effective effect of the drug "drotaverin" on other analgesics was proved.

In patients with intestinal disorders,including irritable bowel syndrome, during the trial of the drug, the positive dynamics of the effect of the drug was similarly observed. 62 patients with constipation and IBS participated in the study. Every day for 2 weeks, the subjects marked their complaints before the beginning of the treatment, then within 2 months taking the Drotaverin tablet 3 times a day. With active treatment, there was a reduction in abdominal pain in 47% of patients. When taking Drotaverine, other symptoms of GI dysfunction decreased.

The effect of the drug "Drotaverin" on the systems and organs of the human body

As mentioned above, the drug "Drotaverin" from which only does not help, it can be used for a variety of diseases.

1. Has moderate sedative, antiischemic andcoronary dilatation. Has a beneficial difference from the "Papaverin", as the latter can reduce the tone, contributing to lowering blood pressure, dizziness and hyperventilation of the lungs.
2. It increases blood flow and greatly reduces the resistance of the vascular system.
3. Does not affect the heart rate index, practically does not change blood pressure. Moderate hypotension can persist for half an hour after intake, no more.
4. It does not affect the autonomic nervous system. In connection with the direct effect of the drug "Drotaverin" on smooth muscle can be used as an anesthetic in cases where the use of anticholinergic agents is contraindicated - with hypertrophy or glaucoma of the prostate gland.
5. After internal administration, the drug begins to act after 2-4 minutes, the maximum effect of the drug is observed in half an hour.
6. Also, the Drotaverin drug is activeelement in chronic lung diseases, hemodynamics, favorably affects the normalization of the functional state of myocardial contractility.
7. It is able to improve the blood supply of tissues, since it has a vasodilating effect.

If there is no analogue of Drotaverin in the pharmacy, the following can be chosen: Spacovin, Sporaverin, Spazmonet Forte, Spazmol, Ple-Spa, Nosh-bras, No-shpa.

Side effects of the drug

In the cardiovascular system:

• Enhanced palpitations.
• Feeling of heat.
• With intravenous administration, blood pressure may drop.
• Development of AV blockade.
• Arrhythmia.

In the respiratory system:

• With intravenous injection, the respiratory center is depressed.

Among others it can be noted:

• Intensified sweating.
• Dizziness.

Who should not take it

The drug "Drotaverin", from which he only does nothelps, but in some cases the doctor can prohibit its reception. Contraindications to the use of the drug "Drotaverin" are the period of pregnancy and lactation. Also, the medicine is canceled if there is an increased sensitivity to the components of the formulation.

The presence of any action of the drug ona pregnant woman was not identified. The appointment means "Drotaverinum" is possible only after a medical assessment of the potential risk to the fetus and positive effect for Mom. Clinical studies in the lactation period have not been conducted, therefore the prescription of the drug during the period of breastfeeding is undesirable.

Overdose

When taking the drug above the established rate, an overdose may occur, accompanied by the following symptoms:

• Heart failure.
• Paralysis of the respiratory center.
• AV blockade.
• Vascular insufficiency.
• Inhibition of breathing.
• Nausea.
• Vomiting.
• Increased sweating.
• Pale skin.

If any of these symptoms or a part of them are found, the doctor should be called immediately.

Can it be assigned to children

A single dose for oral administration is 10-20 mg for children younger than 6 years, 20 mg for 6-12 years, with a frequency of 1-2 times per day.

With increased caution should be takendrug with arterial hypotension. During intravenous administration of the substance, the patient must always be in a prone position, because of the danger of collapse.

Other benefits of taking the drug

Advantage can be considered that wheninternal ingestion of a drug at a therapeutic dose is in no way an obstacle to driving or any other potentially dangerous activity. However, after intravenous administration, it is still recommended not to drive the vehicle for a while, for about 1 hour.

Announced research data and ownthe doctors' observations prove that the drug "Drotaverin" is a highly effective antispasmodic agent, suitable for extensive use in various therapies. Depending on the dosage and form of release of the drug "Drotaverin" the price can fluctuate from 10 to 50 rubles.