Anisocytosis of erythrocytes in the general blood test: indicators

Any stressful conditions for the body are foundits reflection in the processes taking place in it. Be it a hike into the mountains at a sufficiently high altitude or a banal deficit of any vitamin in the diet. Consider what an anisocytosis of red blood cells is.

Definition of anisocytosis

An anisocytosis is called a pathological process,flowing in the body under the influence of a number of factors and changes in the qualitative composition of cells. This changes the size of these bloody cells. Normally, the size boundaries of red blood cells are in the range from 7 to 9 micrometers with the presence of a small number of cells, the sizes of which go beyond these boundaries. Therefore, it is considered a normal physiological process if in addition to 70% of the erythrocytes of the correct qualitative composition, 15% of blood cells with a smaller size are also detected, and this percentage of blood cells, but already large.

Classification

Pathology can be in two versions:

• Anisocytosis of erythrocytes.
• Anisocytosis of platelets.

It is also possible to manifest in two forms:

• Anisocytosis, observed during pregnancy.
• Anisocytosis in children.

Let's try to understand what it is - anisocytosis of red blood cells.

What happens to red blood cells?

Norms of the size of red blood cells (socalled erythrocytes), as we have already found, are in the range of 7 to 9 micrometers. If the size of the cells is less than these values, then such red blood cells are called microcysts (the value of their diameter is less than 6.9 micrometers). If their size is larger than the established norm, then such bloody bodies are called either macrocytes (diameter reaches 12 micrometers) or megalocytes (their numerical value even exceeds 12 micrometers).

Therefore, to identify which bloodycorpuscles have a predominant significance and is diagnosed: microcytosis, macrocytosis, or a mixed type of anisocytosis (combining the characteristics of both the first and second types). The indicator of anisocytosis of erythrocytes is their size.

Each of these isolated pathologies hastheir reasons for development. So, if the patient is diagnosed with microcytosis, we can assume that he has some chronic disease, for example, liver disease, or his body needs iron or vitamin B 12. If, on the contrary, the patient is laboratory confirmed that there is a macrocytosis, it is necessary to immediately identify the causative factor and take all the necessary measures to cure.

We examined the anisocytosis of erythrocytes. But there is another situation.

Changes in the size of platelets

This process can be observed when precipitating, combining or lacking any connections in the body. Most often this is caused by various myeloproliferative changes in the body:

• With leukemia.
• With anemia.
• With radiation sickness.
• With viral diseases.
• With myelodysplastic syndrome.
• With Niman's disease, the peak.

Etiological reasons

What causes can lead to deviations of this kind:

• These include eating disorders - most oftenthis is a lack of vitamins and minerals, leading to a lack of iron in the body, as well as vitamins B12 and A. Since vitamin B12 and iron are involved in the formation of red blood cells, their deficiency leads to the development of an anemic picture. Vitamin A supports the process of stabilizing the size of blood cells.
• Blood transfusion - before transfusionblood it is necessary to thoroughly study it to determine the size. The donor's body can not immediately cope with the sudden arrival of a large number of blood cells of abnormal size - this will be stressful for him.

In the presence of tumors, especially those localized inbone marrow, the process of changing the size of cells begins. The presence of the myelodysplastic process causes the formation of various-blooded blood cells.

This is anisocytosis. What is it, we dismantled.

Degrees of gravity

There are several degrees of severity of pathology:

• Light (minor), in which the number of modified cells does not exceed 0.25 or 25%, respectively.
• Moderate (moderate severity) - the percentage of such cells reaches 50%.
• Expressed - the amount is more than 50%, but less than 75% of the percentage of normal cells.
• A pronounced (fourth degree) - the number of such cells reaches 100%.

Is the anisocytosis of red blood cells dangerous? Increased this figure can be in children.

Anisocytosis in children

Detection of newborns inmacrocytosis indices is a physiological process, during the next few months the blood cells take their normal position. As well as in pregnant women, megalocytosis is detected, which is physiologically conditioned and does not require any specific treatment.

In addition, in the blood of an absolutely healthy child, there is also an insignificant number of microcytes and macro-cells, as well as in the adult population.

Children are more prone to developing this pathological condition due to a greater lack of iron-containing foods and vitamins.

In children, the anisocytosis of erythrocytes (the norm we have examined) is not so often.

Treatment

Therapy begins with the elimination of the underlying disease, which was the source of development of qualitative characteristics of blood cells.

The basis of treatment of this pathology isetiopathogenetic therapy. So if the cause of anisocytosis is folio-deficiency or iron deficiency anemia, then it is necessary to treat these diseases first of all, that is, those diseases that led to this pathological process. Whether low anisocytosis of erythrocytes or high.

Treatment in this case should includebalanced and rational nutrition enriched either with iron (with iron deficiency anemia) or with vitamins of group B. These are legumes, veal, prunes, dried apricots, however, it must be remembered that certain foods can not be combined, since in these cases some vitamins may not be absorbed . For example, tannins contained in strong tea suppress the absorption of iron. Drugs with IDA are iron-containing drugs ("Ferrum-Lek"), and folic acid in case of folic acid anemia ("Cyanocobolamine" at a dosage of 500 milligrams intramuscularly).

Conclusion

In some situations, treatment is notit is recommended, since this process of changing the size of blood cells is temporary, and possibly also physiological, for example in children or in pregnant women.

However, it must be remembered that therapy is prescribed only by a doctor and individually. Self-medication is unacceptable and can lead to serious complications.

We have considered in detail the anisocytosis of erythrocytes.