What is the analogue of "Buskupan" cheap and effective? The list of analogues of "Buskopan"

The drug "Buskopan" on the pharmacological effectbelong to the group of M-holinoblokatorov, and their use is associated with spasmolytic effect. The list of indications for this medicine is quite extensive, which is due to its versatility and relative safety. What is Buscupan used for and what is its effect? How can I replace this drug?

Form of issue

The medicine can be purchased in the form of two variations: tablets and candles. The first form is used for oral administration, after which the active substance is absorbed into the blood in the digestive tract and then exerts its effect on the receptors. Suppositories (or suppositories) are administered rectally. This ensures a rapid absorption into the vast network of blood vessels located in the rectum - the effect comes faster than with the intake of tablets. The price is 320-340 rubles.

How to explain the effect?

The active substance is hyoscine butyl bromide, itrefers to holinoblokatoram, that is, suppresses the function of M-cholinergic receptors, which are located on the postsynaptic membrane. As a result of binding with them, the ability of smooth muscle cells to decrease is reduced, due to which the spasmolytic effect is observed. This allows you to use the medicine for a number of pathologies. An additional action is a decrease in gland secretion, which occurs due to the effect of the drug on the smooth muscle cells of their ducts. There is no anticholinergic effect on the central nervous system, since the drug is a quaternary ammonium product that is unable to penetrate the blood-brain barrier. This is different "Buskopan" - analogues have a different mechanism of action.

Indications

The drug is recommended for patients with pathological conditions accompanied by spasm of smooth muscles. Among such diseases and syndromes:

• colic (intestinal, renal, biliary);
• holicystitis;
• dyskinesia of the biliary tract, as well as the gallbladder itself;
• pilorospasm;
• exacerbation of peptic ulcer (as a component of complex treatment).

Often doctors prescribe tablets "Buskopan" (analogs will help to replace the medicine).

Side effects

The additional effect of the drug is associated withinfluence on the receptors of other anatomical formations. On the part of the sense organs, paralysis of accommodation, dilatation of the pupils (this is manifested by photophobia), as well as an increase in intraocular pressure are observed. Reduces the tone of not only the target organs, but also others, including the expansion of the bronchi. Unusually effect on cardiomyocytes - taking medications of this group provokes tachycardia. In connection with a decrease in the activity of the glands, dry skin and mucous membranes, including xerostomia, are observed. Frequent constipation and delay urination.

Contraindications

Additional effects cause a number of contraindications. These include:

• intolerance of components;
• angle-closure glaucoma;
• tachycardia;
• hyperplasia of the prostate;
• pronounced xerostomia;
• pulmonary edema;
• myasthenia gravis;
• age up to 6 years.

"Buscopan": instructions for use

Analogues have their own characteristics and canused according to another scheme. Tablets "Buskopan" are taken orally 3 times a day, washed down with a lot of water. Candles injected with a pointed end into the rectum. A single dose is determined by the attending physician and depends on the individual characteristics of the patient. Usually, 1 or 2 tablets / suppositories are prescribed.

Buskopan: analogues

At the moment there is a large numberdrugs that have an antispasmodic effect. Each of them has its own characteristics, which should be read before the reception. Often there is no possibility to use tablets and candles "Buskopan". Analogues can only be used after consultation with a doctor.

"Spazmolitin"

The drug is actively used in gastroenterology,having an antispasmodic effect. It is used primarily for colic. Also among the additional indications: angina pectoris, sciatica, migraine and neuritis. The active substance of the drug is adiphenine. It is able to block not only muscarinic (M), but also nicotinic receptors, that is, it is a non-selective cholinoblocker. This property extends the list of side effects. In addition, "Spasmolitin" has a pronounced effect on the central nervous system, which makes it absolutely contraindicated in glaucoma. The dosage should be adjusted by the attending physician. As a rule, appoint 0.05-0.1 g 3-4 times a day. Cases of overdose were recorded quite rarely and were marked by such symptoms as nausea, dizziness and headache. Due to the pronounced influence on the central nervous system, one should refrain from managing transportation and doing any work that requires concentration of attention during the period of taking the drug. An alternative is drugs that do not work on the central nervous system. For example, the well-known analogue described above is Buskopan. Currently, the drug is rarely used, given preference to selective blockers.

"Galidor"

The basis of antispasmodics is bicyclic fumarate. The drug is available in the form of tablets and a solution for injection. The advantage of the second form is the highest bioavailability. The medicine penetrates directly into the blood, due to which the spasmolytic effect comes in the shortest possible time. In addition to reducing the tone of smooth muscle organs, dilated blood vessels are observed. This is associated with the ability to block calcium channels, as well as with antiserotonin action. The range of application of "Galidor" is higher than the analogue "Buskopan" differs from it. This drug as an antispasmodic is used for gastrointestinal and urological diseases, accompanied by a spasm of smooth muscles. The vasodilator effect makes it possible to use it in diseases of peripheral vessels - spasm, obliteration. Also, "Halidor" is often used in cerebral ischemia. The medicine has the following contraindications:

• hypersensitivity to components;
• renal, respiratory or hepatic impairment of severe severity;
• epilepsy;
• recent hemorrhagic stroke;
• pregnancy and breastfeeding;
• age to 18 years;
• severe cardiac pathologies (acute myocardial infarction, insufficiency in the stage of decompensation, antrioventricular blockade).

Due to a large list of contraindications, takingpreparation is allowed only with the permission of the doctor. It is not necessary to use it during pregnancy and lactation due to the lack of clinical data, despite the fact that there was no direct pathological effect on the fetus. The price is 300-400 rubles for 50 tablets.

"Papaverine"

This is another analogue of Buskupan. The spasmolytic and hypotensive effect of the drug is associated with the peculiarities of pharmacodynamics. The drug has an inhibitory effect on phosphodiesterase, due to which cAMP accumulates in cells, and the level of calcium ions decreases. In this regard, the tone of the smooth muscles of the organs and vessels decreases. Reduction of blood pressure is due to the vasodilating effect. The drug should not be used for glaucoma, antrioventricular blockade, severe hepatic insufficiency. Also it is contraindicated for children under 6 months. In the elderly, taking "Papaverin" can cause hyperthermia. Data on safety for pregnant women are not available.

Often patients can not purchase Buscopan. Analogues are cheaper to solve this problem. Price "Papaverine" - 50 rubles for 20 tablets.

Spasmolytics are actively used for treatmentdiseases of the digestive tract, genitourinary system and other pathologies. Which analogue to choose? Buscupan has a number of substitutes that have similar properties, but they differ in instructions for use, pharmacodynamics and a list of side effects and contraindications. Before choosing any drug of this group, you should consult a specialist.